Oncology · 2025
A brake on cancer growth
A protein complex shuts down the cell’s protein-making machinery and stops triple-negative breast cancer cells from dividing: a new angle on a hard-to-treat cancer.
Notes on cancer
All notes on cancer
Why triple-negative breast cancer is so hard to treat
Most breast cancers have a target. This one is defined by what it lacks.
Ribosomes: the factory every cancer depends on
Cancer cells grow fast. To do that, they need to build proteins at an enormous rate.
Senescence: the cells that refuse to die
Some cells stop dividing but never leave. That can protect us from cancer, and slowly harm us too.
Releasing the brakes: a Nobel Prize for cancer immunotherapy
James Allison and Tasuku Honjo showed that blocking the immune system’s brakes can unleash it against cancer.
The first CAR-T approval turns living cells into cancer drugs
The FDA has approved a therapy that re-engineers a patient’s own immune cells to attack leukemia.
CRISPR is Science’s Breakthrough of the Year: what it means for the lab bench
Gene editing just became cheap, fast and precise. For cell biologists, that changes the questions we can ask.