Dr. Younes Medkour, scientist, biologics & drug delivery, Montréal
Skin aging and extracellular vesicles
With age, skin loses collagen, and its outer barrier keeps out most of the ingredients meant to help. I use extracellular vesicles to carry anti-aging actives past that barrier.
Extracellular vesicles as drug carriers
Carriers built from particles that cells release: ProbioVesicle, from probiotic yeast at Nanomère, for anti-aging actives in the skin, and a chemotherapy carrier with the Brett lab at Concordia.
A brake on tumour growth
A three-protein complex shuts down growth in triple-negative breast cancer, one of the hardest forms to treat.
I 
develop extracellular vesicles as carriers for skin aging and drug delivery, from loading the active to potency and immune testing. It builds on years of research on aging, oncology and metabolism.
When the immune system remembers the carrier
A drug carrier can work on the first dose and fail on the second. The reason is immune memory.
How an EV drug carrier is developed
- LoadLoad the payload into the vesicle.
- DeliverReach the target cells.
- PotencyConfirm the payload works in cell-based assays.
- ImmunogenicityShow that the immune system tolerates it.
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University courses, free on YouTube
Full courses in genetics, genomics, molecular biology and nutrition, taught mechanism first.
Scientist, biologics & drug delivery
From target biology in oncology and metabolism to drug delivery R&D. Researcher, lecturer, and co-founder of Nanomère.
What changes when research becomes a company
In the lab, the question is “is it true?” In a company, it is “is it true every time?”
Why yeast is the best aging model you’ve never heard of
Bread yeast has quietly shaped what we know about how cells work, and how they age.
Biotech, explained
Short notes on drug development, delivery, oncology and aging: what a new result means and what it doesn’t.
